Atracurium in whole body hyperthermia

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Determination of continuous atracurium infusion rate in dogs undergoing whole-body hyperthermia.

Infusion rates for atracurium were calculated from multiple bolus injection data for normothermic (38 degrees C; n = 4) and hyperthermic (42 degrees C; n = 14) dogs anesthetized with thiopental and oxymorphone while undergoing whole-body hyperthermia treatment. The calculated infusion rate for atracurium at 38 degrees C was 6.2 +/- 0.3 micrograms/kg/min and the calculated infusion rate at 42 de...

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Protocol for long duration whole body hyperthermia in mice.

Hyperthermia is a general term used to define the increase in core body temperature above normal. It is often used to describe the increased core body temperature that is observed during fever. The use of hyperthermia as an adjuvant has emerged as a promising procedure for tumor regression in the field of cancer biology. For this purpose, the most important requirement is to have reliable and u...

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Splanchnic tissues undergo hypoxic stress during whole body hyperthermia.

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Whole body hyperthermia to 42°Cwas induced in five normal beagles, using a humidityand temperature-controlled chamber. Core temperatures of 41.2-43.0°C were achieved in 50 min and maintained for 60 min. Cardiopulmonary responses included marked tachypnea and tachycardia. Blood gases underwent progressive drops in both PO2(mean, 117 torr) and PC02 (mean, 22 torr), suggesting the possibility of...

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ژورنال

عنوان ژورنال: Anaesthesia

سال: 1990

ISSN: 0003-2409,1365-2044

DOI: 10.1111/j.1365-2044.1990.tb14654.x